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What is Advantix for dogs?

Advantix for Dogs, also known as K9 Advantix, is a popular parasitic treatment for fleas, ticks and lice.

A topical treatment is often favorited by pet owners as the product is not absorbed into the dog’s bloodstream, instead it works when the parasite comes into contact with the skin. Advantix kills existing adult fleas, as well as killing new adult fleas as they emerge, helping to break the breeding cycle. Advantix also kills and repels ticks including the brown dog tick (Rhipicephalus sanguineus), the deer tick (Ixodes ricinus) and the paralysis tick.

Your dog is also protected from the irritation of biting insects, as Advantix kills lice, and repels mosquitos, sandflies and stable flies.


  • Fast acting – starts killing fleas in 20 minutes
  • Effective – kills and repels
  • Waterproof formula remains active even when your dog gets wet
  • Safe for use on pregnant and lactating dogs

Is Advantix suitable for my dog?

Advantix spot-on solution is suitable for dogs and puppies from 7 weeks of age, with a minimum body weight of 3.5 pounds (1.5 kg).  This product is safe for use with pregnant and lactating dogs. Advantix is a canine product only and is harmful to cats.

Dosage Schedule

Advantix for Dogs should be applied every four weeks for the control of fleas and most ticks, or every two weeks for the control of paralysis ticks. The exact product used depends on the weight of your dog or puppy.

Body weight Pipette size (ml) Total Imidacloprid (mg Total Permethrin (mg)
Under 8.8 lbs (4 kg) 0.4 40 200
8.8-22 lbs (4-10 kg) 1.0 100 500
22-55 lbs (10-25 kg) 2.5 250 1250
Over 55 lbs (25 kg) 4.0 400 2000

What are the side effects of Advantix?

Side effect reported in dogs treated with Advantix may include transient skin sensitivity or lethargy. Less common reactions reported are behavior changes, gastrointestinal symptoms and neurological signs.

What precautions must be taken?

  • For canine use only – do not use on cats
  • For topical use only.
  • Wash hands thoroughly after application.
  • Do not allow cats to groom the treated dog for at least 48 hours.
  • Not for use on dogs under 7 weeks of age.
  • Not for use on dogs weighing less than 3.5 pounds (1.5 kg).

How effective is Advantix (Imidacloprid + Permethrin)?

The product remains effective if the animal becomes wet. However, prolonged, intense exposure to water should be avoided. In cases of frequent water exposure the persistent efficacy may be reduced. In these cases do not retreat more frequently than once weekly. If a dog requires a shampoo, it should be administered before applying Advantix or at least 2 weeks after application, to optimize efficacy of the product.

Brand Comparison

Advantix Flea & Tick Treatment

Sort By
Advantix Dogs 8.8-22lbs (4-10kg) - 12 Pack
Advantix Dogs Over 55lbs (25kg) - 12 Pack
Advantix Dogs 22-55lbs (10-25kg) - 12 Pack
Advantix Dogs Under 4kg 8.8lbs (4kg) - 12 Pack
Advantix Dogs Over 55lbs (25kg) - 4 Pack
Advantix Dogs 8.8-22lbs (4-10kg) - 4 Pack
Advantix Dogs 22-55lbs (10-25kg) - 4 Pack

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    D. Debell
    Ollie's Flea Free!
    Works like a charm! Picky eater, so would not take oral prevention. Doesn't even know he's got it on.
    L. Mitchell
    I put it on my dog and forget about any danger of getting unwanted bugs on her

    Nadine Adams
    It is great. No more fleas
    Gerry Carrigan
    It is a great product at a great price. Mailing time was very quick. Thanks!
    Gerry Carrigan
    It is a great product at a great price. Mailing time was very quick. Thanks!