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Revolution vs Trifexis

Compare Revolution Spot-On to Trifexis Tablets

Combining a flea treatment with a heartworm preventative can make managing your pet’s health easier and more convenient. This broad-spectrum option is possible with topical or oral treatments.

Revolution spot-on provides month long protection against heartworm, fleas, ticks and ear mites. It also controls sarcoptic mange in dogs, and prevents hookworms and roundworms in cats.

Trifexis tablets for dogs prevent heartworm, and treat and control hookworm, ringworm and whipworm. They also kill fleas at all life stages: adults, eggs and larvae, but do not kill ticks.

Revolution spot-on is recommended for use in dogs at least 6 weeks of age, and cats at least 8 weeks of age.Trifexis is safe for use with dogs and puppies at least 8 weeks of age, weighing 5 lbs (2.3kg) minimum. Do not give Trifexis tablets to cats.

Top tip: Fleas and ticks can carry nasty diseases, but protecting your pet doesn’t need to be difficult. Use our comparison chart to weigh up the pros and cons of the most popular products.

  Revolution Trifexis
Kills Fleas yes tick yes tick
Repels Fleas - -
Kills Flea Eggs and Larvae Prevents flea eggs from developing yes tick
Kills Ticks yes tick -
Repels Ticks - -
Kills and/or Repels Mosquitoes - -
Prevents Heartworm yes tick yes tick
Prevents Roundworms yes tick
Cats only
yes tick
Prevents Hookworms yes tick
Cats only
yes tick
Prevents Whipworms - yes tick
Other Parasites Treats and controls ear mites and sarcoptic mange  
Safe for Pregnant or Nursing Pets yes tick -
When does it starts working More than 98% of adult fleas are killed within 36 hours Kills fleas within 30 minutes; kills 100% of fleas within 4 hours
Application Topical Beef-flavored tablet
Active Ingredient(s) Selamectin Spinosad, Milbemycin Oxime
Dosage Monthly Monthly

Revolution vs Trifexis

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Revolution For Dogs 5-10lbs (2.6-5kg) - 12 Pack
$102.95
$140.30
Revolution For Dogs 10-20lbs (5-10kg) - 12 Pack
$111.95
$154.90